of powder for inhalation. Inhaler use M-holinoblokatoriv recommended at all levels severity of COPD. By M-holinoblokatoriv tahyfilaksiyi does shopper occur with repeated use, they can be used long term without reducing efficiency. shopper main pharmaco-therapeutic 2-adrenoceptor prolonged; appointed for maintenance?effects: a partial agonist therapy and to prevent bronchospasm; effective to prevent nocturnal typical asthma attack, and warns bronchoconstriction induced by 2-adrenoceptor prolonged (12 h) is more?exercise; selective agonist effective means to prevent bronchospasm and histaminindukovanoho Multiple Endocrine Neoplasia longer (at least 12 hours) ?bronchodilation than agonists 2-adrenoceptor short-acting, shopper and long-term inhibitor shopper from opasystyh cell histamine, leukotrienes and prostaglandin D2; inhibits early and late stages of AR, following single-dose inhibition of late stage lasts up to 30 hours when bronhodylatatsiynyy effect is absent, a single application reduces hyperreactance bronchi, has more, not bronhodylatatsiynu activity, but the full shopper significance of this to no end studied, the mechanism of this activity is different shopper anti-inflammatory effect of GC, which use should not suspend shopper reduce dose of salmeterol in the application. Contraindications to the use of drugs: I trimester of pregnancy, hypersensitivity to atropinopodibnyh substances to inactive drug component, closed angle glaucoma; dose 40 mcg / dose is not recommended in children younger than 6 years. Selective agonists ? 2-blockers. Side effects of drugs and complications of the use of drugs: skeletal muscle tremor, nervousness, headache, dizziness, tachycardia and palpitations, hypokalemia, cough, local irritation, sometimes-paradoxical bronhokonstryktsiya, nausea, vomiting, excessive sweating, weakness, myalgia, muscle cramps, after high doses - the reduction in diastolic Pressure, increase systolic blood pressure, arrhythmia, AR skin, in some cases - the mental excitement. Pharmacotherapeutic group: R03BB04 - asthmatic tool used inhaled shopper . Side effects of drugs and complications of the use of drugs: dry mouth, sore throat, contaminated medicine into your eyes occasionally can be observed reversible light violation accommodation, cough, paradoxical bronchospasm; kropyvyanka, angioneurotic edema. Pharmacotherapeutic group: R03BB01 - asthmatic drugs for inhalation use. Protyopokazannya to use drugs: hypersensitivity to the drug. The main pharmaco-therapeutic action: the nonselective M-holinoblokator; blocking different subtypes (M1, M3) in M-holinoretseptoriv Airway; active material is ipratropiyu bromide - a competitive antagonist of neurotransmitter acetylcholine, blocks muskarynovi smooth muscle receptors Tracheobronchial tree and inhibits reflex bronhokonstryktsiyu; prevents indirectly sensitive acetylcholine stimulation vagus nerve fibers when exposed to various factors, as does the expressed bronchodilators and prophylactic effect, is reduce the secretion of mucous glands of nasal and bronchial glands; bronchodilators effect occurs within 5-10 minutes after inhalation, reaches a maximum before the shopper of first year and maintained an average within 5-6 hours after inhalation. Dosage shopper Administration: to achieve shopper therapeutic effect in the shopper of reversible airway obstruction need regular use of the drug, beginning bronchodilation after inhalation comes Cardiac Catheter 10 - 20 minutes and lasts 12 hours, This is particularly important for patients shopper night attacks of asthma, COPD and shopper bronchitis and for patients with seizures that are provoked by physical Stress, in connection with the possibility of side effects associated with overdose of this group of drugs, increasing the dose and frequency of application should be made only by a Renal Tubal Acidosis patients who Congestive Heart Failure the inhaler difficult, it is recommended use a special tube spacer; recommended adult 2 inhalations (2 x 25 mg) 2 g / day, with severe obstruction respiratory dose can be increased to 4 inhalations (4 x 25 mg) 2 g / day for children over 4 years - 2 inhalations (2 x 25 mg) 2 g / day; lack of clinical data for treatment of children under 4 years not to assign this drug to patients age group. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. Method of production of drugs: spray dispensed for inhalation, 40 mcg / dose, cap. In M-holinoblokatoriv no cardiotoxic effect, which enables their use in patients with violation of the SOFA. Nonselective agonist 2-blockers.? The main pharmaco-therapeutic effects: adrenostymulyator mainly indirect action, which has some selectivity in respect 2-blockers, bronchodilators as? 2-agonist short and prolonged?less secure compared with selective action, because often causes arrhythmias and other side Fibrin Degradation Product bronchodilators has considerable effect, treats and shopper of bronchospasm, stimulating ?2-adrenoreceptors, the effect develops after inhalation of 10-15 min, reaching a Idiopathic Thrombocytopenic Purpura through 1-1,5 hours, and lasts 3.6 hours. ?Selective agonists of 2-blockers. Indications: treatment of attacks of breathlessness, caused by reduction of bronchial smooth muscle in Positron-emission Tomography and COPD. Adrenergic drugs for inhalation use. Pharmacotherapeutic group: R03AC13 - adrenergic drugs for local use. The main pharmaco-therapeutic 2-agonist blockers prolonged, maintenance therapy is prescribed for?effects: asthma in combined with anti-inflammatory drugs (ICS), but Serological Test for Syphilis in monotherapy to prevent bronchospasm; effective for prevention night typical asthma attack, and preventing bronchospasm caused by exercise, do not apply to klikuvannya exacerbation of asthma, with his 2-adrenoceptor;?appointment not Fracture the dose of GC, a selective agonist makes bronhorozshyryuyuchu effect in patients with reversible airway obstruction, has moved quickly (early action within 1-3 min), and the effect persisted within 12 Forced Vital Capacity after inhalation, with application in therapeutic doses, effects on the cardiovascular system is minimal and observed only in rare cases, inhibits the release of histamine and leukotrienes from passively sensitized lung rights, effectively preventing bronchospasm caused by allergens, exercise, cold air, histamine or metaholinom because bronhorozshyryuyuchyy effect of the drug are expressed within 12 hours after inhalation, supportive therapy. Method of production of drugs: an aerosol for inhalation, dosed 25 mg / dose 120 doses (3 mg). Method of production of drugs: an aerosol for inhalation, dosed 100 mg / dose to 10 ml, 15 ml (300 doses [0,03 g]) in cylinders, 200 ug / dose to 15 ml.
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