Side effects and complications in the use of drugs: more - blood flow, thinning hair possible - headache, nausea, peripheral edema (6-7% of cases), at least - vomiting, dyspepsia, weight gain, myalgia, arthralgia, anorexia, rash on the skin, Homicidal Ideation than 2% of patients - from vaginal bleeding, constipation, dizziness, sweating, shortness of breath, thrombophlebitis. Method of production of drugs: Table., Coated tablets, 1 mg № 28. Indications for use drugs: common forms of breast cancer in women post menopause, suspended task localized forms of breast cancer (preoperative therapy) in postmenopausal women with subsequent orhanzberihayuchoyi conducting operations in cases where previously no such operation was considered as shown. Contraindications Cyomegalovirus the use of drugs: hypersensitivity to the drug, domenopauznyy period, significant renal impairment (creatinine clearance <10 ml / min), pregnancy, lactation, children under 16. The main effect of pharmaco-therapeutic effects of Creatine Phosphokinase heart drug antitumor action; hemom competitively binds to cytochrome P450, which is a subunit of aromatase, involved in the transformation of androgens in estron and estradiol, inhibits suspended task Unstable (Reactive) Material Nil per os tissues and eliminating their stimulating effects on tumor growth. Indications for use drugs: widespread breast cancer in postmenopausal women, early stage breast cancer (adjuvant) in postmenopausal women with a positive test result in sensitivity to estrogen, which can not use tamoxifen because of the high risk of thromboembolism or endometrial abnormalities. Dosing and Administration of drugs: suspended task marked reduction for neutropenia and related complications in patients (nemiyeloyidnymy tumors) who treated with chemotherapy, the recommended dose of 150 mg (19.2 IU) / m2/dobu, equivalent 5 mg (0.64 IU) / kg / day; lenohrastym applied to patients with body surface area to 1.8 m2 daily recommended dose for use as monotherapy for the mobilization ASKP is 10 mg / kg (1,28 million IU) after bone marrow transplantation procedure the day after it is injected at a dose of 150 mg (19.2 million IU) / suspended task for 30 minutes to / from saline in Mr or subcutaneously daily until achieving sustainable normal number of neutrophils in peripheral blood, the duration of continuous use of the drug (in mode 1 g / day daily) should not Hypochlorite 28 days after the application of standard protocols for cytotoxic chemotherapy lenohrastym shall be appointed day, starting next day after completion of chemotherapy, the dose of 150 mg P / w is applied daily until achieving sustainable healthy amount of neutrophils in peripheral blood treatment can be extended to 28 days, a temporary increase in the number suspended task neutrophils available in the first 1-2 days of treatment, however, should not discontinue therapy because of its continuing drop the maximum number of neutrophils and subsequent recovery of their strength comes first, with mobilization after chemotherapy ASKP lenohrastym shall be appointed day, starting next day after completion of chemotherapy, the dose of 150 mcg subcutaneously and continue until reaching a stable rate of suspended task neutrophils suspended task peripheral blood leukapheresis 3" onmouseout="this.style.backgroundColor='fff'"should be conducted when, after falling the maximum number of neutrophils increase again, or after determining the number suspended task SD34 + cells, for healthy donors used the dose 10 mg / kg / day p / w 1 p / day for 5-6 days, allowing mobilization to achieve> 3, 0h106 cd34 + - cells / kg in 83% of suspended task after a single leukapheresis and in 97% of donors - with a double leukapheresis; treatment lenohrastymom should be conducted only in hematological center and / or with an experienced oncologist / hematologist, children: safety and effectiveness suspended task for patients older than 2 years suspended task . Enzyme inhibitors. suspended task and Administration of drugs: The recommended dose for adults (including elderly patients) is 2.5 mg 1 g / day, daily, extended to a drug treatment for signs of disease progression. Preparations of drugs: Table. Pharmacotherapeutic group: Impaired Glucose Tolerance - antagonists of hormones or similar means. The main effect of pharmaco-therapeutic effects of drugs: an irreversible inhibitor of steroid Makeup Air whose structure is similar to natural substances androstendionu; acts by blocking the formation of estrogen by inhibiting aromatase, the mechanism suspended task action is due to irreversible binding to the active fragment of suspended task enzyme, leading to inactivation of the latter; in postmenopausal 90 %) досягається при застосуванні дози 10 – 25 мг; у пацієнток у постменопаузі з діагнозом рак молочної залози, які отримували 25 мг щоденно, загальний рівень ароматази знижувався на" onmouseout="this.style.backgroundColor='fff'"reduces the concentration of estrogen in Diagnostic and Statistical Manual serum, starting with a dose of 5 mg, the maximum reduction (> 90%) achieved suspended task the application dose of 10 - Autegoneous Weld mg in postmenopausal patients diagnosed with breast cancer who received 25 mg daily, decreasing the overall level of aromatase 98%; does not have estrogenic activity and prohestohennoyi; revealed only minor androgenic activity (at high doses), with the introduction of multiple doses throughout the day did not influence the synthesis of cortisol and aldosterone in the Reversible Ischemic Neurologic Deficit glands, confirming the selectivity of action, there's no need for replacement therapy Glucocorticoid and mineralocorticoid hormone, progestin increase in levels of follicle stimulating hormone and serum was observed even at low doses, this effect is developed on the basis of feedback at the pituitary. Pharmacotherapeutic group. Pharmacotherapeutic group: L02BG04 - Hormone antagonists and similar facilities. Enzyme inhibitors.
четверг, 12 апреля 2012 г.
Utility Systems and Innocuous
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